Learn More About Cancer
and Available Treatment Options
Every Cancer Is Unique
Cancer occurs when the DNA in a human cell becomes damaged or mutates in such a way that the body is unable to identify the problem or repair it. These abnormal cells can grow out of control and form tumors or masses that invade healthy tissue and organs. Traditionally, cancer has been categorized according to its location in the body, such as lung cancer, breast cancer, etc., and most patients with a particular tumor type were treated with the same chemotherapies.
In recent years, cancer researchers have identified specific genes that are related to cancer growth. As a result, cancer can now be categorized by the underlying changes in DNA, or genomic alterations that drive the tumor’s growth.
Targeted therapy is a promising type of cancer treatment that precisely identifies and attacks cancer cells by locating the specific genomic alterations that are driving the cancer growth. These therapies attack only cancer cells and do in general far less damage to normal cells. Targeted therapy is a growing part of many cancer treatment regimens.
Genomic testing or profiling identifies the underlying DNA alterations that are driving the tumor’s growth. This information may help physicians understand which targeted treatment options are available for a patient based on their tumor’s unique genomic profile.Click here to read frequently asked questions.
Find Out How Genomic Profiling a Tumor
Can Help You
Comprehensive genomic profiling can help tailor your treatment options
As discussed above, even when two people have tumors in the same part of their body, their tumors are most likely different at a basic, molecular level – that is, there may be different genomic alterations causing each person’s cancer to grow.
Comprehensive genomic profiling cancer tests such as FoundationOne and FoundationOne Heme provide the information your physician needs in one single test to help guide a tailored treatment approach using targeted therapies. You and your doctor can use the results from FoundationOne or FoundationOne Heme to discuss possible treatment options, including FDA-approved targeted therapies or novel targeted treatments under development in clinical trials.
Talk to your doctor about comprehensive genomic profiling and learn how you may benefit from a tailored treatment approach.
Your Doctor Orders The Test
If you and your doctor decide FoundationOne or FoundationOne Heme is right for you, your doctor will place an order for the appropriate test. Foundation Medicine will work with your doctor to have your tumor sample sent to our laboratory where it can be examined for genomic alterations.
You may have questions about the cost of the test, and whether it is covered by your insurance. Our FoundationACCESS program is designed to help you and your doctor’s office with these questions as well as guide you in accessing targeted therapies prescribed for you.Click here to read frequently asked questions.
...there comes a day when the doctor tells you we found something that might help your case. And all of a sudden there is new hope.- Heather, FoundationOne Patient
How Does Comprehensive
Genomic Profiling Work?
Foundation Medicine results gave me hope. I was able to get a targeted therapy based on my genomic profile that worked for my cancer type.- Joyce Stern, FoundationOne Patient
A passionate group of cancer genomics experts here to help you
Once your tumor sample is received at the Foundation Medicine laboratory, the DNA from the tumor will be taken from the sample so we can identify the genomic alterations that are unique to your cancer. Typically, Foundation Medicine sends your physician a detailed report, with information about your tumor’s genomic makeup and potential treatment options within 14 days for FoundationOne and within 21 days for FoundationOne Heme.
FoundationOne and FoundationOne Heme reports are designed to help your physician match your results with available therapies that target your specific cancer, as well as any open clinical trials that are testing new targeted treatments. Everything in the report is supported by up to date clinical findings and scientific research.Click here to read frequently asked questions.
Inside the FoundationOne Report
Targeted Therapies Matched To Your Unique Profile
Results of FoundationOne and FoundationOne Heme can reveal multiple genomic alterations that are driving the growth of your cancer, along with targeted therapies that may work for your cancer. These targeted therapies are FDA approved either for your tumor type or for another tumor type. You and your doctor can evaluate the data available in the context of your unique situation to determine which treatment options may be right for you.Click here to download questions to ask your doctor
Clinical Trials May Be An Option For You
You may be a candidate for a clinical trial or study evaluating a potential new targeted therapy. Clinical trials are often an important option for patients with cancer, particularly if an approved treatment has stopped working or your cancer has progressed or returned following treatment. Targeted therapies represent the most active area of cancer research today, so an investigational treatment in a clinical trial may very well be a good treatment for your cancer. may very well be a good treatment for your cancer.
FoundationOne and FoundationOne Heme reports include a list of ongoing clinical trials you may be eligible for, as well as tell you how you and your doctor can find additional studies as they open.Preview sample report
At Foundation Medicine, we understand that when you or a loved one is battling cancer, the financial burden should be the last thing you worry about.
FoundationACCESS has been developed to address any financial, access and claim issues for FoundationOne and FoundationOne Heme testing. Our FoundationACCESS billing and reimbursement services, as well as FoundationACCESS Careline, are designed to deliver the promise of comprehensive genomic profiling to patients regardless of financial situation.
FoundationACCESS Reimbursement and Financial Assistance Program
Foundation Medicine is committed to helping you and your doctor navigate your cancer and not worry about how to pay for the test. When your physician orders FoundationOne or FoundationOne Heme, he or she will provide your insurance information to Foundation Medicine. We will work directly with your insurance company on your behalf to try to obtain coverage and pursue any necessary appeals. Through FoundationACCESS, we also offer financial assistance programs to work within your ability to pay.
Foundation Medicine is committed to patients with cancer and ensuring they have access to prescribed therapy. In partnership with the non-profit ‘Patient Advocate Foundation’, Foundation Medicine provides the FoundationACCESS Careline, a service to help you obtain access to prescribed cancer treatments based on your FoundationOne or FoundationOne Heme test results.
If you or your doctor is having difficulty obtaining prescribed therapy, the FoundationACCESS Careline may help. When you enroll, you’ll be matched with a case manager who will provide you with individualized case management services to help access the therapy by working with your insurance company, the pharmaceutical company that markets the drug, or through other available funding.
Your doctor’s office may contact the FoundationACCESS Careline regarding your prescribed cancer treatment. A case manager will then call you to get the process started. To learn more about Patient Advocate Foundation, visit www.patientadvocate.org.